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General Hospital 2-week spoilers for Sept 22 - Oct 03, 2025 find key characters like Britt Westbourne (Kelly Thiebaud), Tracy Quartermaine (Jane Elliot), and Monica Quartermaine (Leslie Charleson) take center stage in this period. A huge development is the shocking return of Nathan West (Ryan Paevey) and the debut of Monica's sister, played by Erika Slezak.

Spoilers for General Hospital anticipate that Britt will find herself in a predicament, while Tracy stumbles upon old photos of Monica, leading to a nostalgic moment. Meanwhile, Lucy Coe (Lynn Herring) faces Tracy's wrath when she arrives uninvited at the Quartermaine mansion. Brooklyn 'BLQ' Quartermaine (Amanda Setton) hints at a change in Quartermaine rules to Cody Bell (Josh Kelly). 

More GH spoilers find Anna Devane (Finola Hughes) uncovers surprising information, causing a stir among Dante Falconeri (Dominic Zamprogna), Lucas Jones (Van Hansis), and Elizabeth Webber (Rebecca Herbst). A heart-rending moment looms as Sonny Corinthos (Maurice Benard) and Carly Corinthos Spencer (Laura Wright) receive upsetting news related to Monica's passing. 

General Hospital spoilers look at Lulu Spencer (Alexa Havins) as she seeks to mend ties with Britt for the sake of Rocco Falceroni (Finn Carr). Anna ropes in Nina Reeves (Cynthia Watros) to discuss her adoptive brother Nathan's return. Meanwhile, Trina Robinson (Tabyana Ali) confronts her father, Curtis Ashford (Donnell Turner), about a possible budding romance with Jordan Ashford (Tanisha Harper) the weeks of 09/22-10/03, 2025. 

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